منابع مشابه
Pyridoxine-dependent epilepsy initially responsive to phenobarbital.
Pyridoxine-dependent epilepsy is a rare autosomal recessive disorder characterized by recurrent seizures that are not controlled by anticonvulsant medications but remits after administration of pyridoxine. We report on a 30 day-old girl who presented with seizures during the first day of life, initially responsive to anticonvulsant therapy, which remitted within two weeks. Seizures were charact...
متن کاملThe impact on cognition by phenobarbital in epilepsy treatment
Despite the development of successive generations of antiepileptic drugs, phenobarbital has retained a unique position in the therapeutic armamentarium and is still the most widely prescribed treatment for epilepsy worldwide. Although serious systemic side effects of phenobarbital are uncommon, its potential neurotoxicity remains a major concern. This is particularly so in the developed world. ...
متن کاملP20: Computational Model for the Effects of Phenobarbital and the NKCC1 Inhibitor Bumetanide in the Pilocarpine Model of Temporal Lobe Epilepsy
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متن کاملEffect of Chronic Administration of Phenobarbital, or Bromide, on Pharmacokinetics of Levetiracetam in Dogs with Epilepsy
BACKGROUND Levetiracetam (LEV) is a common add-on antiepileptic drug (AED) in dogs with refractory seizures. Concurrent phenobarbital administration alters the disposition of LEV in healthy dogs. HYPOTHESIS/OBJECTIVES To evaluate the pharmacokinetics of LEV in dogs with epilepsy when administered concurrently with conventional AEDs. ANIMALS Eighteen client-owned dogs on maintenance treatmen...
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ژورنال
عنوان ژورنال: BMJ
سال: 2004
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.329.7476.1199